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The role of MRI scanning prior to prostate biopsies
A pair of articles currently scheduled for publication in the December issue of the Journal of Urology has just appeared on line under the title “MRI before prostate biopsy — yes or no?” Unfortunately...
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Intervew with three leading researchers at the NCI
Many readers may be interested in having a look at the text based on a recent interview carried out with four clinicians who specialize in research into the management of prostate cancer at the...
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Does prostatic inflammation increase risk for prostate cancer?
A new paper just published in Cancer, and based on information from patients gathered during the REDUCE study has suggested that men who have acute and/or chronic inflammation of the prostate on biopsy...
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Mapping biopsies vs mpMRI vs Prostate Histoscanning technology
According to a recently published article, European researchers are initiating a new study to explore the ability of multi-parametic MRIs (mpMRI) and the Prostate HistoScanning™ (PHS) technique to rule...
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Understanding the complexities of MRI-targeted biopsies
A recent video-discussion on the OncLive web site addresses the complexities in the evolution of application of multiparametric MRI scanning and MRI/TRUS fusion biopsies in the diagnosis of early stage...
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Let’s compare the media hype to the actual data (about MR-guided biopsy)
According to an article online in The Australian today, “Men won’t need to have numerous painful needles in their rectum to find out if they have prostate cancer anymore”. However, the article is short...
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What to make of a PCA3 score of ≥ 100
Some studies (e.g., this one by Roobol et al.) have previously indicated that not all men with very high prostate cancer antigen 3 (PCA3) scores are necessarily found to have prostate cancer on biopsy...
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Early data on the accuracy and potential of the 4Kscore test
The late-breaking abstract for the results of a US-based study of the accuracy of the new 4Kscore Test™ has just been made available on line. (Thank you to one of our correspondents for bringing this...
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Another potential genomic test for prostate cancer aggression
In a presentation given last Saturday at the annual meeting of the European Society for Radiotherapy and Oncology (ESTRO) in Vienna, a Canadian research team introduced yet another potential test that...
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MRI- and MRI/TRUS fusion-guided biopsy: an up-to-date review
The first issue of the new journal Urology Practice includes a very nice review of the use of MRI imaging in the evaluation, diagnosis, and biopsy of men with prostate cancer. Raskolnikov et al. (the...
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MRI/TRUS fusion-guided biopsy in a community-like urology practice
A new study just reported in the Journal of Urology provides information on the application of MRI/TRUS fusion-guided prostate biopsy to diagnose prostate cancer in a community-like urology practice...
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Risk for 120-day prostate biopsy-specific mortality — redux
Once upon a time (not so very long ago) Boniol et al. suggested that the 120-day mortality rate associated with biopsies for risk of prostate cancer might be as high as 1.3 percent. This caused...
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“Extreme apical sampling” and prostate cancer diagnosis
A new article in the September issue of Prostate addresses the potential benefits of “extreme apical sampling” during the initial biopsies of men at risk for prostate cancer based on such standard...
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Data from two large cohorts of Austalian patients on active surveillance
A new paper in BJU International reports on data from a total of 650 Australian patients managed on active surveillance for low-risk, localized prostate cancer. The study data reported by Thompson et...
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Prospective data on the use of MRI-guided vs. TRUS-guided biopsy
Two newly published papers in the November issue of the Journal of Urology address prospective studies of the use of differing forms of MRI-guided biopsy in the diagnosis of prostate cancer. Quentin et...
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MRI/TRUS fusion biopsies in men with PSA values < 5.2 ng/ml
There is a distinctly “odd” paper in the December 2014 issue of the Journal of Urology on optimization of the use of MRI/TRUS fusion-guided biopsies in men suspected of having prostate cancer. This...
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A new “gold standard” for detection of prostate cancer?
An article just published in the Journal of Urology argues that, ” The gold standard for cancer detection in primary biopsy is [now] a combination of systematic and targeted cores.” The article, by a...
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Music (plus lidocaine) soothes the savaged male
A small, randomized, pilot study has shown that music (along with some lidocaine) reduces the anxiety, pain, and dissatisfaction of men having a TRUS-guided biopsy compared to the lidocaine alone....
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Can invasive procedures spread prostate cancer?
Prostate cancer is seldom spread by invasive procedures such as biopsies, prostatectomy, TURP, LDR brachytherapy, HDR brachytherapy, or insertion of fiducials for image-guided radiotherapy. We know...
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First and second biopsies and their diagnostic accuracy
A paper by Wong et al. published in December carries the title, “Diagnostic prostate biopsy performed in a non-academic center increases the risk of re-classification at confirmatory biopsy for men...
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